張經(jīng)濤
[摘要] 目的 研究腹腔鏡手術(shù)精索靜脈曲張治療后的生育能力恢復(fù)。方法 隨機(jī)選取2014年8月—2016年8月淄博市計(jì)劃生育技術(shù)指導(dǎo)中心男性科收治的精索靜脈曲張患者60例,采用SPSS 21.0將入組患者按先后序列號(hào)(1~60)隨機(jī)分為2組:一組腹腔鏡精索靜脈高位結(jié)扎術(shù)治療組(腹腔鏡手術(shù)組,30例),一組開腹腹膜后精索靜脈高位結(jié)扎術(shù)治療組(開腹手術(shù)組,30例),統(tǒng)計(jì)分析兩組患者的精子密度、活動(dòng)率、畸形率、手術(shù)時(shí)間、術(shù)后腸功能恢復(fù)時(shí)間、住院時(shí)間、術(shù)后并發(fā)癥發(fā)生情況。 結(jié)果? 腹腔鏡手術(shù)組患者的精子密度、活動(dòng)率(26.4±3.6)×106/mL、(55.7±3.3)%均顯著高于開腹手術(shù)組(18.8±2.7)×106/mL、(32.0±4.2)%(t=6.965,4.541,P<0.05),畸形率(64.1±4.3)%顯著低于開腹手術(shù)組(80.2±6.1)%(t=4.365,P<0.05)。腹腔鏡手術(shù)組患者的雙側(cè)手術(shù)時(shí)間、住院時(shí)間(40.4±10.1)min、(3.1±1.0)d均顯著短于開腹手術(shù)組(63.3±15.2)min、(7.2±2.4)d(t=4.303,4.182,P<0.05),但兩組患者的單側(cè)手術(shù)時(shí)間、術(shù)后腸功能恢復(fù)時(shí)間(36.6±8.8)min、(18.5±4.6)h vs(39.4±10.6)min、(15.1±3.5)h之間的差異無統(tǒng)計(jì)學(xué)意義(t=1.886,1.638,P>0.05)。腹腔鏡手術(shù)組、開腹手術(shù)組患者的術(shù)后并發(fā)癥發(fā)生,10.0%(3/30)、13.3%(4/30)之間的差異無統(tǒng)計(jì)學(xué)意義(χ2=1.32,P>0.05)。 結(jié)論 腹腔鏡手術(shù)較開腹手術(shù)精索靜脈曲張治療后更能有效恢復(fù)患者的生育能力。
[關(guān)鍵詞] 腹腔鏡手術(shù);精索靜脈曲張;生育能力
[中圖分類號(hào)] R71? ? ? ? ? [文獻(xiàn)標(biāo)識(shí)碼] A? ? ? ? ? [文章編號(hào)] 1674-0742(2019)05(b)-0038-03
[Abstract] Objective To study the recovery of fertility after varicocele treatment in laparoscopic surgery. Methods A total of 60 patients with varicocele admitted to the male family of Zibo City Family Planning Technical Guidance Center from August 2014 to August 2016 were randomly selected. The patients were randomly assigned to the serial number (1-60) by SPSS21.0 and were divided into two groups of laparoscopic varicocele ligation group(30 cases in laparoscopic surgery group), one group of open laparoscopic varicocele ligation group(open surgery group, 30 cases). The sperm density, activity rate, deformity rate, operation time, postoperative intestinal function recovery time, hospitalization time, and postoperative complications were analyzed statistically. Results The sperm density and activity rate of patients in the laparoscopic surgery group (26.4±3.6)×106/mL and (55.7±3.3)% were significantly higher than those in the open surgery group (18.8±2.7)×106/mL, (32.0±4.2)% (t=6.965, 4.541, P<0.05), the deformity rate (64.1±4.3)% was significantly lower than that of the open surgery group (80.2±6.1)% (t=4.365, P<0.05). The bilateral operation time and hospitalization time (40.4±10.1) min and (3.1±1.0)d in the laparoscopic surgery group were significantly shorter than those in the open surgery group (63.3±15.2)min, (7.2±2.4) d (t= 4.303, 4.182, P<0.05), but the unilateral operation time and postoperative intestinal function recovery time (36.6±8.8) min, (18.5±4.6)h vs (39.4±10.6)min, (15.1±3.5)h, was not significant (t=1.886, 1.638, P>0.05). Postoperative complications occurred in the laparoscopic surgery group and the open surgery group of 10.0% (3/30) and 13.3% (4/30) was not significant (χ2=1.32, P>0.05). Conclusion Laparoscopic surgery can effectively restore the fertility of patients after laparoscopic varicocele treatment.
該研究結(jié)果表明,腹腔鏡手術(shù)組患者的精子密度、活動(dòng)率(26.4±3.6)×106/mL、(55.7±3.3)%均顯著高于開腹手術(shù)組(18.8±2.7)×106/mL、(32.0±4.2)%(t=6.965,4.541,P<0.05),畸形率(64.1±4.3)%顯著低于開腹手術(shù)組(80.2±6.1)%(t=4.365,P<0.05)。腹腔鏡手術(shù)組患者的雙側(cè)手術(shù)時(shí)間、住院時(shí)間(40.4±10.1)min、(3.1±1.0)d均顯著短于開腹手術(shù)組(63.3±15.2)min、(7.2±2.4)d(t=4.303,4.182,P<0.05),但兩組患者的單側(cè)手術(shù)時(shí)間、術(shù)后腸功能恢復(fù)時(shí)間(36.6±8.8)min、(18.5±4.6)hvs(39.4±10.6)min、(15.1±3.5)h之間的差異無統(tǒng)計(jì)學(xué)意義(t=1.886,1.638,P>0.05)。腹腔鏡手術(shù)組、開腹手術(shù)組患者的術(shù)后并發(fā)癥發(fā)生,10.0%(3/30)、13.3%(4/30)之間的差異無統(tǒng)計(jì)學(xué)意義(χ2=1.32,P>0.05),和上述相關(guān)醫(yī)學(xué)研究結(jié)果一致。
綜上所述,腹腔鏡手術(shù)較開腹手術(shù)精索靜脈曲張治療后更能有效恢復(fù)患者的生育能力,值得在臨床推廣應(yīng)用。
[參考文獻(xiàn)]
[1]? 張恒,吳海嘯,徐旻,等.腹腔鏡下2種精索內(nèi)靜脈高位結(jié)扎術(shù)式的臨床效果比較[J].中國(guó)微創(chuàng)外科雜志,2017,17(6):527-530.
[2]? 曹志彬,陳勇輝,王元天,等.腹腔鏡下經(jīng)腹和經(jīng)腹膜外精索靜脈高位結(jié)扎術(shù)式臨床對(duì)照研究[J].中國(guó)男科學(xué)雜志,2017,31(5):50-52.
[3]? 劉健男,劉亞東,楊可來爾,等.精索靜脈曲張外科治療概述及有效性分析[J].現(xiàn)代泌尿外科雜志,2018,23(1):73-76.
[4]? 劉云龍,谷現(xiàn)恩,張曉毅,等.精索靜脈曲張所致陰囊疼痛經(jīng)手術(shù)治療緩解的影響因素Meta分析[J].中華男科學(xué)雜志,2017,23(6):550-560.
[5]? 郭均聰.腹腔鏡精索血管高位集束結(jié)扎術(shù)治療精索靜脈曲張的療效和術(shù)后睪丸發(fā)育情況分析[J].中外醫(yī)療,2016,35(13):13-15,21.
[6]? 馬宏,鄧庶民,吳鵬杰,等.單孔腹腔鏡與顯微外科治療精索靜脈曲張的臨床療效與安全性比較[J].中國(guó)性科學(xué),2018, 27(5):39-42.
[7]? 孫建民.腹腔鏡精索靜脈高位結(jié)扎術(shù)治療精索靜脈曲張的臨床可行性[J].臨床醫(yī)藥文獻(xiàn)電子雜志,2017,4(18):3411, 3414.
[8]? 趙杰,劉鳳青,崔山龍,等.亞臨床型精索靜脈曲張的診療在男性不育癥中的臨床意義[J].臨床醫(yī)藥文獻(xiàn)電子雜志,2017, 4(17):3201.
(收稿日期:2019-02-18)