樂映川
【摘要】 目的:探討輸尿管鏡下鈥激光碎石術(shù)對輸尿管結(jié)石患者術(shù)后康復(fù)及結(jié)石排凈率的影響。方法:選取2018年2月-2019年7月筆者所在醫(yī)院收治的輸尿管結(jié)石患者115例,依照奇偶順序分為研究組(58例)、對照組(57例)。對照組采用輸尿管鏡氣壓彈道碎石術(shù)治療,研究組采用輸尿管鏡下鈥激光碎石術(shù)治療。比較兩組手術(shù)指標(biāo)(手術(shù)時間、術(shù)后血尿持續(xù)時間、住院時間)、結(jié)石排凈率、并發(fā)癥發(fā)生率、應(yīng)激指標(biāo)(血清皮質(zhì)醇、丙二醛水平)。結(jié)果:研究組結(jié)石排凈率為96.55%,高于對照組的75.44%,差異有統(tǒng)計學(xué)意義(P<0.05);研究組手術(shù)時間、術(shù)后血尿持續(xù)時間、住院時間均短于對照組,差異均有統(tǒng)計學(xué)意義(P<0.05);術(shù)后10 min研究組血清皮質(zhì)醇、丙二醛水平均低于對照組,差異均有統(tǒng)計學(xué)意義(P<0.05);研究組術(shù)后并發(fā)癥發(fā)生率為3.45%,低于對照組的17.54%,差異有統(tǒng)計學(xué)意義(P<0.05)。結(jié)論:輸尿管結(jié)石患者采用輸尿管鏡下鈥激光碎石術(shù)治療,能縮短手術(shù)時間,清除結(jié)石,減輕應(yīng)激反應(yīng),促進(jìn)患者早期康復(fù),安全性高。
【關(guān)鍵詞】 輸尿管鏡 鈥激光碎石術(shù) 輸尿管結(jié)石
doi:10.14033/j.cnki.cfmr.2020.15.010 文獻(xiàn)標(biāo)識碼 B 文章編號 1674-6805(2020)15-00-03
Effect of Holmium Laser Lithotripsy under Ureteroscope on Postoperative Recovery and Stone Removal Rate of Patients with Ureteral Calculi/LE Yingchuan. //Chinese and Foreign Medical Research, 2020, 18(15): -26
[Abstract] Objective: To investigate the effect of holmium laser lithotripsy under ureteroscope on postoperative recovery and stone removal rate of patients with ureteral calculi. Method: From February 2018 to July 2019, 115 patients with ureteral calculi in our hospital were selected and divided into the study group (58 cases) and the control group (57 cases) according to parity order. The control group was treated with ureteroscopy pneumatic lithotripsy, while the study group was treated with ureteroscopy holmium laser lithotripsy. The surgical indexes (duration of operation, duration of postoperative hematuria, length of hospital stay), stone removal rate, incidence of complications, and stress indexes (serum cortisol and malondialdehyde levels) of two groups were compared. Result: The stone removal rate of the study group was 96.55%, higher than that of the control group (75.44%), the difference was statistically significant (P<0.05). All the operative time, postoperative hematuria duration time and hospital stay time in the study group were shorter than those in the control group, the differences were statistically significant (P<0.05). At 10 minutes after operation, the serum cortisol and malondialdehyde levels in the study group were lower than those in the control group, the differences were statistically significant (P<0.05). The incidence of postoperative complications in the study group was 3.45%, lower than that in the control group (17.54%), the difference was statistically significant (P<0.05). Conclusion: Holmium laser lithotripsy under ureteroscope can shorten the operation time, clear the calculi, reduce the stress response, promote the early recovery of patients with ureteral calculi, with high safety.
皮質(zhì)醇、丙二醛水平是臨床反映應(yīng)激反應(yīng)常見生化指標(biāo),其水平越高表明機(jī)體應(yīng)激損傷程度越高[12]。本研究顯示,術(shù)后10 min研究組血清皮質(zhì)醇、丙二醛水平均低于對照組(P<0.05),表明輸尿管結(jié)石患者采用輸尿管鏡下鈥激光碎石術(shù)治療,能減輕應(yīng)激反應(yīng)。此外,輸尿管鏡下鈥激光碎石術(shù)對術(shù)者專業(yè)技術(shù)要求較高,其應(yīng)熟練掌握輸尿管鏡及鈥激光操作技巧,動作輕柔,以減少對輸尿管及其他組織損失,保證手術(shù)效果;同時在采用輸尿管鏡查探管腔時,若出現(xiàn)視野受限,未能完全看清整個管腔時,應(yīng)退出輸尿管鏡,適當(dāng)調(diào)整角度,再繼續(xù)前進(jìn)查探病灶情況;操作時應(yīng)確保降低膀胱內(nèi)壓,充分麻醉,以防出現(xiàn)輸尿管抱鏡現(xiàn)象,輸尿管退鏡困難,導(dǎo)致發(fā)生輸尿管損傷。
綜上可知,輸尿管結(jié)石患者采用輸尿管鏡下鈥激光碎石術(shù)治療,能縮短手術(shù)時間,清除結(jié)石,減輕應(yīng)激反應(yīng),促進(jìn)患者早期康復(fù),安全性高。
參考文獻(xiàn)
[1]王正權(quán),陶沙,黃小七,等.輸尿管開口電切術(shù)聯(lián)合輸尿管鏡治療輸尿管結(jié)石16例[J].安徽醫(yī)藥,2019,23(5):923-925.
[2]孫永凱.輸尿管鏡氣壓彈道碎石術(shù)治療輸尿管結(jié)石的臨床分析[J].中國冶金工業(yè)醫(yī)學(xué)雜志,2019,36(3):322-323.
[3]袁順輝,楊德林,李志鵬,等.筋膜擴(kuò)張器協(xié)助輸尿管鏡鈥激光治療嬰幼兒中下段輸尿管結(jié)石的療效觀察[J].中國內(nèi)鏡雜志,2018,24(1):93-95.
[4]王健宇,胡宗陽,陶朝發(fā),等.經(jīng)尿道輸尿管鏡下鈥激光碎石術(shù)治療輸尿管結(jié)石的臨床療效觀察[J].局解手術(shù)學(xué)雜志,2018,27(1):44-46.
[5]王洪兵,李康慧,平峰.三金片聯(lián)合ESWL治療輸尿管結(jié)石(濕熱蘊(yùn)結(jié))的臨床研究[J].中華中醫(yī)藥學(xué)刊,2019,37(6):1417-1420.
[6]姚增民,白志杰,王新勝,等.NMSCT輸尿管重建聯(lián)合腎血流圖診斷輸尿管結(jié)石[J].中國中西醫(yī)結(jié)合外科雜志,2019,25(2):179-182.
[7]許清江,葉烈夫,朱慶國,等.輸尿管壁厚度對嵌頓性輸尿管結(jié)石的預(yù)測價值[J].中華泌尿外科雜志,2019,40(3):210-214.
[8]儲傳敏,楊煒,楊啟維,等.鎳鈦合金泌尿系統(tǒng)取石網(wǎng)在輸尿管鏡碎石術(shù)中的臨床應(yīng)用[J].中華航海醫(yī)學(xué)與高氣壓醫(yī)學(xué)雜志,2017,24(4):315-318.
[9]楊鐘良,黃毅.輸尿管鏡下鈥激光碎石與氣壓彈道碎石術(shù)治療輸尿管結(jié)石的療效比較[J].解放軍預(yù)防醫(yī)學(xué)雜志,2019,37(5):71-72.
[10]高永濤,閆波,高恩江.自擬三金排石湯輔助輸尿管軟鏡下鈥激光碎石術(shù)治療腎結(jié)石臨床療效分析[J].山西醫(yī)藥雜志,2018,47(6):673-674.
[11]顧日輝,劉麗芳.經(jīng)皮腎鏡結(jié)合輸尿管軟鏡鈥激光碎石術(shù)治療復(fù)雜性腎結(jié)石的療效分析[J].首都食品與醫(yī)藥,2019,26(24):19-20.
[12]梁蘇東,呂高飛,阮亞石,等.輸尿管軟鏡碎石術(shù)與經(jīng)皮腎鏡碎石術(shù)對腎結(jié)石患者炎性因子、氧化應(yīng)激及應(yīng)激激素水平的影響[J].海南醫(yī)學(xué)院學(xué)報,2017,23(20):2783-2786.
(收稿日期:2020-01-17) (本文編輯:馬竹君)