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腹腔鏡結(jié)直腸癌根治術(shù)對患者圍術(shù)期機體代謝及胃腸功能的影響分析

2020-05-25 02:43徐眾
中外醫(yī)療 2020年3期
關(guān)鍵詞:結(jié)直腸癌開腹手術(shù)圍術(shù)期

徐眾

[摘要] 目的 分析研討腹腔鏡結(jié)直腸癌根治術(shù)對患者圍術(shù)期機體代謝及胃腸功能的影響。方法 從該院2018年1月—2019年1月期間收治的結(jié)直腸癌患者中隨機抽取92例進(jìn)行討論,按治療方式分組研究組(46例腹腔鏡結(jié)直腸癌根治術(shù)治療)和對照組(46例開腹手術(shù)治療),觀察比較治療狀況,如圍術(shù)期胃腸功能、脂代謝、蛋白代謝等。結(jié)果 術(shù)前脂代謝、蛋白代謝指標(biāo)差異無統(tǒng)計學(xué)意義(P>0.05);研究組LDL-C術(shù)后2 d(1.46±0.12)mmol/L、5 d(1.31±0.12)mmol/L、10 d(2.31±0.22)mmol/L時優(yōu)于對照組(1.71±0.15)mmol/L、(1.64±0.14)mmol/L、(1.88±0.16)mmol/L,術(shù)后2 d TC(2.98±0.21)mmol/L、TG(0.94±0.08)mmol/L、術(shù)后5 d TC(2.62±0.18)mmol/L、TG(0.88±0.07)mmol/L高于對照組2 d TC(2.42±0.17)mmol/L、TG(0.82±0.06)mmol/L、5 d TC(2.15±0.14)mmol/L、TG(0.71±0.04)mmol/L,術(shù)后2 d、5 d、10 d CER[(0.27±0.02)g/L、(0.22±0.03)g/L、(0.37±0.05)g/L)]、TRF[(2.85±0.22)g/L、(2.61±0.17)g/L、(3.36±0.05)g/L)]、PA[(243.17±19.86)mg/L、(235.85±19.22)mg/L、(257.81±23.18)mg/L)]高于對照組2 d、5 d、10 d CER[(0.21±0.02)g/L、(0.15±0.02)g/L、(0.25±0.02)g/L)]、TRF[(2.31±0.16)g/L、(2.16±0.15)g/L、(3.02±0.22)g/L)]、PA[(225.46±18.31)mg/L、(210.03±16.32)mg/L、(234.25±20.06)mg/L)](P<0.05)。組間術(shù)前胃腸功能指標(biāo)差異無統(tǒng)計學(xué)意義(P>0.05),研究組術(shù)后2 d、5 d、10 d VIP低于對照組,GAS、CCK高于對照組(P<0.05)。結(jié)論 與開腹手術(shù)比較,腹腔鏡結(jié)直腸癌根治術(shù)治療結(jié)直腸癌疾病更為適合,此方式對患者圍術(shù)期脂代謝、胃腸功能、蛋白代謝等指標(biāo)的影響較小,有利于術(shù)后康復(fù)。

[關(guān)鍵詞] 結(jié)直腸癌;腹腔鏡;開腹手術(shù);結(jié)直腸癌根治術(shù);圍術(shù)期

[中圖分類號] R735.3 ? ? ? ? ?[文獻(xiàn)標(biāo)識碼] A ? ? ? ? ?[文章編號] 1674-0742(2020)01(c)-0016-04

Effect of Laparoscopic Radical Resection of Colorectal Cancer on Body Metabolism and Gastrointestinal Function during Perioperative Period

XU Zhong

Department of General Surgery, Haixiya Hospital of Shanxian County, Heze, Shandong Province, 274300, China

[Abstract] Objective To analyze and discuss the effect of laparoscopic radical resection of colorectal cancer on metabolism and gastrointestinal function during perioperative period. Methods 92 patients with colorectal cancer admitted to the hospital from January 2018 to January 2019 were randomly selected for discussion. They were divided into study group (46 cases of laparoscopic radical resection of colorectal cancer) and control group (46 cases of open surgery). The treatment status, such as perioperative gastrointestinal function, lipid metabolism and protein metabolism, were observed and compared. Results There was not statistically signifiant difference in preoperative lipid metabolism and protein metabolism indexes before surgery(P>0.05). The LDL-C of the study group was lower at 2 d (1.46±0.12) mmol/L, 5 d (1.31±0.12) mmol/L, and 10 d (2.31±0.22) mmol/L better than the control group (1.71±0.15) mmol/L, (1.64±0.14) mmol/L, and (1.88±0.16) mmol/L. At 2 d, TC (2.98±0.21) mmol/L, TG (0.94±0.08) mmol/L, 5 d, TC (2.62±0.18) mmol/L, TG (0.88±0.07) mmol/L, TG (0.82±0.06) mmol/L, 5 d, TC (2.15±0.14) mmol/L, TG (0.71±0.04) mmol/L, Postoperative CER[ (0.27±0.02) g/L, (0.22±0.03) g/L, (0.37±0.05)g/L], TRF [(2.85±0.22) g/L, TRF (2.61±0.17) g/L, (3.36±0.05) g/L], PA[ (243.17±19.86) mg/L, (235.85±19.22) mg/L, (257.81±23.18) mg/L] at 2 d, 5 d and 10 d were higher than those in the control group[ CER(0.21±0.02) g/L, (0.15±0.02) g/L, (0.25±0.02) g/L)], TRF[(2.31±0.16) g/L, (2.16±0.15) g/L, (3.02±0.22) g/L], PA [(225.46±18.31) mg/L, (210.03±16.32) mg/L, (234.25 ±20.06) mg/L](P<0.05). There was not statistically significant difference in preoperative gastrointestinal function indexes between groups(P>0.05). At 2 d, 5 d and 10 d after surgery, the VIP of the study group was lower than that of the control group, and GAS and CCK were higher than that of the control group (P<0.05). Conclusion Compared with open surgery, laparoscopic radical resection of colorectal cancer is more suitable for the treatment of colorectal cancer. This method has less influence on perioperative lipid metabolism, gastrointestinal function, protein metabolism and other indicators

綜上所述,與開腹手術(shù)比較,腹腔鏡結(jié)直腸癌根治術(shù)治療結(jié)直腸癌疾病更為適合,此方式對患者圍術(shù)期脂代謝、胃腸功能、蛋白代謝等指標(biāo)的影響較小,有利于術(shù)后康復(fù)。

[參考文獻(xiàn)]

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[4] ?吳文生. 腔鏡結(jié)直腸癌根治術(shù)對結(jié)直腸癌患者臨床療效及胃腸功能的影響[J].檢驗醫(yī)學(xué)與臨床,2017,14(Z1):300-302.

[5] ?高王軍, 李福廣.腹腔鏡結(jié)直腸癌根治術(shù)對結(jié)直腸癌患者臨床療效及胃腸功能的影響[J]. 癌癥進(jìn)展,2016,14(9):910-912.

[6] ?丁海濤, 帕爾哈提·阿布都熱衣木,韓智君,等.結(jié)直腸癌NOSE術(shù)對患者氧化應(yīng)激、免疫功能及機體微炎癥的影響[J]. 中國現(xiàn)代手術(shù)學(xué)雜志, 2017, 21(1):9-13.

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(收稿日期:2019-10-23)

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