涂智毅 楊志明 何濤 鄒天士
[摘要]目的 研究支氣管肺泡灌洗對(duì)肺膿腫及支氣管擴(kuò)張合并感染患者肺功能的影響。方法 選取2017年1月~2018年1月我院收治的84例肺膿腫及支氣管擴(kuò)張合并感染患者作為研究對(duì)象,采用隨機(jī)分組方法分為對(duì)照組(42例)與實(shí)驗(yàn)組(42例)。對(duì)照組患者接受常規(guī)藥物治療,實(shí)驗(yàn)組患者接受支氣管肺泡灌洗治療,比較兩組患者治療后的肺功能、治療效果和不良反應(yīng)。結(jié)果 治療后,實(shí)驗(yàn)組患者的用氣呼吸量(FVC)、一秒鐘最大呼氣量(FEV1)、最大呼氣流量(PEF)高于對(duì)照組患者,差異有統(tǒng)計(jì)學(xué)意義(P<0.05)。實(shí)驗(yàn)組患者的治療總有效率高于對(duì)照組患者,差異有統(tǒng)計(jì)學(xué)意義(P<0.05)。實(shí)驗(yàn)組的不良反應(yīng)總發(fā)生率低于對(duì)照組,差異有統(tǒng)計(jì)學(xué)意義(P<0.05)。結(jié)論 肺膿腫和支氣管擴(kuò)張合并感染患者接受支氣管肺泡灌洗治療,能夠有效改善患者的肺部功能,值得推廣應(yīng)用。
[關(guān)鍵詞]肺膿腫;支氣管擴(kuò)張;感染;支氣管肺泡灌洗;肺功能
[中圖分類號(hào)] R562.2+2? ? ? ? ? [文獻(xiàn)標(biāo)識(shí)碼] A? ? ? ? ? [文章編號(hào)] 1674-4721(2019)2(c)-0078-03
[Abstract] Objective To study the influence of bronchoalveolar lavage on pulmonary function in patients with pulmonary abscess and bronchiectasis complicated with infection. Methods A total of 84 patients with pulmonary abscess and bronchiectasis complicated infection who were admitted to our hospital from January 2017 to January 2018 were selected as the research objects. The patients were divided into the control group (42 cases) and the experimental group (42 cases) by randomized method. Patients in the control group received conventional drug therapy, and patients in the experimental group received bronchoalveolar lavage. The lung function, treatment effect and adverse reactions of the two groups were compared. Results After treatment, the level of breathing volume (FVC), maximum expiratory volume in one second (FEV1), maximum expiratory flow (PEF) of the experimental group were higher than those of the control group, the difference was statistically significant (P<0.05). The total effective rate of the experimental group was higher than that of the control group, the difference was statistically significant (P<0.05). The total incidence of adverse reactions in the experimental group was lower than that in the control group, the difference was statistically significant (P<0.05). Conclusion Patients with pulmonary abscess and bronchiectasis combined with bronchoalveolar lavage can effectively improve the lung function of patients, which is worthy of popularization and application.
[Key words] Lung abscess; Bronchiectasis; Infection; Bronchoalveolar lavage; Pulmonary function
肺膿腫和支氣管擴(kuò)張合并感染是臨床上常見(jiàn)的呼吸系統(tǒng)疾病,此病在臨床上具有較高的發(fā)病率,且患者發(fā)病后,病情較為嚴(yán)重,對(duì)患者的危害較大[1]。肺膿腫及支氣管擴(kuò)張合并感染會(huì)對(duì)患者的肺部功能造成嚴(yán)重?fù)p傷,能夠引發(fā)患者出現(xiàn)氣胸、胸悶、氣喘、呼吸困難和呼吸衰竭的癥狀,且合并感染會(huì)對(duì)患者的多處器官造成傷害,嚴(yán)重危及患者的身體健康,因此需要對(duì)患者進(jìn)行及時(shí)有效的治療,以改善患者的肺部功能,提升患者的生存質(zhì)量[2]。本研究主要研究支氣管肺泡灌洗對(duì)肺膿腫及支氣管擴(kuò)張合并感染患者肺功能的影響,現(xiàn)報(bào)道如下。
1資料與方法
1.1一般資料
選取2017年1月~2018年1月在我院接受治療的84例肺膿腫及支氣管擴(kuò)張合并感染患者作為研究對(duì)象,根據(jù)患者接受治療方法的不同分為對(duì)照組與實(shí)驗(yàn)組,各42例。對(duì)照組中,男26例,女16例;年齡為43~74歲,平均(58.43±5.26)歲;其中肺膿腫患者20例,支氣管擴(kuò)張合并感染患者22例。實(shí)驗(yàn)組中,男27例,女15例;年齡為44~75歲,平均(59.47±5.30)歲;其中肺膿腫患者21例,支氣管擴(kuò)張合并感染患者21例。納入標(biāo)準(zhǔn):所有患者均確診為肺膿腫及支氣管擴(kuò)張合并感染;所有患者均無(wú)治療禁忌證[3]。排除標(biāo)準(zhǔn):伴有嚴(yán)重心、肝、肺等嚴(yán)重器質(zhì)性的患者;伴有嚴(yán)重精神疾病和認(rèn)知障礙的患者[4]。所有患者均知情,并自愿接受相關(guān)治療和研究,患者自愿簽訂知情同意書(shū),兩組患者的一般資料比較,差異無(wú)統(tǒng)計(jì)學(xué)意義(P>0.05),具有可比性。