THE AMERICAN JOURNAL OF PSYCHIATRY Volume 173 · Number 10 · October 2016

EDITORIALS

949 Early Detection of Psychosis Vulnerability: Progress, Opportunity, and Caution

William T. Carpenter

951 Putting Psychosis in Its Place

Ian Kelleher, Mary Cannon

953 Sustaining the Long-Term Effects of Supported Employment for Persons With Psychiatric Disabilities

Susan R. McGurk, Kim T. Mueser

956 Children of Depressed Parents: The Long View

Constance Hammen

INTROSPECTION

958 Compassion in the Eye of the Beholder

Ira Lesser

TREATMENT IN PSYCHIATRY

960 Treatment Controversies in Adult ADHD

James J. McGough

IMAGES IN PSYCHIATRY

967 Edward Cowles (1837–1919)

Richard Noll, Kenneth S. Kendler

REVIEWS AND OVERVIEWS

969 Prevention of Firearm Suicide in the United States: What Works and What Is Possible

J. John Mann, Christna A. Michel

ARTICLES

980 An Individualized Risk Calculator for Research in Prodromal Psychosis

Tyrone D. Cannon

989 Personalized Prediction of Psychosis: External Validation of the NAPLS-2 Psychosis Risk Calculator With the EDIPPP Project

Ricardo E. Carrión

997 The Bidirectional Associations Between Psychotic Experiences and DSM-IV Mental Disorders

John J. McGrath

1007 Long-Term Effects of Evidence-Based Supported Employment on Earnings and on SSI and SSDI Participation Among Individuals With Psychiatric Disabilities

Judith A. Cook

1015 Mixed Depression in Bipolar Disorder: Prevalence Rate and Clinical Correlates During Naturalistic Follow-Up in the Stanley Bipolar Network

Shefali Miller

1024 Offspring of Depressed Parents: 30 Years Later

Myrna M. Weissman

1033 Hyperresponsiveness of the Neural Fear Network During Fear Conditioning and Extinction Learning in Male Cocaine Users

Anne Marije Kaag

LETTERS TO THE EDITOR

1043 Effects of Ultra-Low-Dose Buprenorphine on Suicidal Ideation Confounded by Physical Pain Relief?

Xiulu Ruan, et al.

1043 Ultra-Low-Dose Buprenorphine for Mental Pain: Response to Ruan et al.

Yoram Yovell, Gali Bar

1044 Detrimental Side Effects of Repeated Ketamine Infusions in the Brain

Kenji Hashimoto

1045 Antidepressant Efficacy and Dosing Comparisons of Ketamine Enantiomers: Response to Hashimoto

Jaskaran B. Singh

1046 Down-Regulation of SIRT1 Gene Expression in

Major Depressive Disorder Xiong-Jian Luo, Chen Zhang,

BOOK FORUM

1047 Marijuana and Mental Health

1048 People With Mental Illness in the Criminal Justice System: Answering a Cry for Help