Special Issue on‘‘Biomarkers for Diseases’’

The journalGenomics Proteomics&Bioinformatics(GPB)is now inviting submissions for a special issue(to be published in the winter of 2015)on the topic of‘‘Biomarkers for Diseases’’.

As an emerging index,disease biomarkers have demonstrated the potential application in diagnosis and prognosis.The detection of the disease indicators at molecular level,DNA, RNA,protein or metabolites,could gain highly sensitive and specific signals that truly reflect the pathological changes and fully facilitate diagnostic analysis at early phase with invasive mode.Revolution of high-throughput techniques,such as genome-sequencing and mass spectrometers,greatly promotes the discovery and application of the disease biomarkers.The existing disease biomarkers have covered nearly all the macromolecular categories as well as their variants and modifications,including predisposing genetic variations(such as SNPs), mutations,epigenetic modifications,miRNAs,splice isoforms,abnormal proteins and autoantibodies.Although some biomarkers have been adopted in clinical practice,there are still great needs for studies on identifying new ones,understanding the existing ones and applying the well-studied ones in practice.

We are pleased to announce a special issue on‘‘Biomarkers for Diseases’’in GPB,which is likely to provide a platform for the quality papers focusing on biomarker discovery and application.Dr.Siqi Liufrom Beijing Institute of Genomics,Chinese Academy of Sciences andDr.Edwin Wangfrom the National Research Council Canada are Guest Editors of this issue.The topics may include(but not be limited to):

? Discovery of disease biomarkers using next-generation sequencing

? Epigenetic evidence and disease biomarkers

? Discovery of disease biomarkers through evaluation of gene expression

? Exploration and application of disease protein biomarkers using proteomic analysis

? Alternation of metabolic pathways responding to disease

? Integration of omics data for discovery of disease biomarkers

? High-throughput platforms for biomarker discovery

? Techniques for measurement of disease biomarkers in the clinical diagnosis

Original studies,reviews,methods,application notes,etc.are all welcome.The portfolio will be open for incoming manuscripts tillSeptember 30,2015.

Manuscripts can be submitted online at http://ees.elsevier.com/gpb/.The Guide for Authors is also available on this web site.Note to mention that the submission is for this special issue.

For further information,please contact us:

Dr.Liu(siqiliu@big.ac.cn);

Dr.Wang(Edwin.Wang@cnrc-nrc.gc.ca);

Editorial Office(editor@big.ac.cn).